Tomosyn's tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction, incluiding their ability to engage in a form of plasticity

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How do pollutants and other chemicals that we are exposed to affect our health? Researchers have applied a method to identify the proteins in the body affected by chemicals. The method can be used to discover at an early stage whether a substance has biological effects in an organism.

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The bacterium Pseudomonas aeruginosa is resistant to all antibiotics on the market. Therefore, there is a great need for new therapeutic approaches. In order to find them, it helps to understand how the germ reacts to active substances.

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Scientists have discovered a new route to produce complex antibiotics exploiting gene editing to re-program pathways to future medicines urgently required to combat antimicrobial resistance, treat neglected diseases and prevent future pandemics.

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An international team of scientists has linked increased air pollution to an uptick in cases of lung adenocarcinoma (LADC) worldwide. The same study also concluded an overall lower consumption of tobacco worldwide is statistically linked to less people contracting lung squamous cell carcinoma (LSCC).

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In part of a recent human study led by the Technical University of Munich (TUM), it was found that after eating a curry dish containing pepper, piperine - an alkaloid responsible for the pungency of pepper - was present in the milk of breastfeeding women. The findings help decipher mechanisms that shape our food preferences from infancy.

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Prostate cancer screening results differ in men taking cholesterol-lowering statin drugs compared with non-users, a study finds. In statin users, screening did not increase the incidence of prostate cancer as it did in other men.

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Researchers have made a major discovery in understanding motor neuron disease (MND). The research team has found that MND has 4 distinct patterns of changes in electrical signals that can be identified using EEG (electroencephalography).

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By understanding the epidemiology and population biology of a significant and high-priority pathogen, Enteroccocus faecium (E. faecium) in Irish hospitals, researchers are providing the evidence base for more effective surveillance, and infection and prevention control strategies aimed at minimizing the spread of the antibiotic resistant bacteria.

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Researchers have explored the brain neuronal mechanism that allows the perception of familiar images even if they are indistinct. They found that the number of neurons responding to low-contrast rather than high-contrast visual stimuli increased in rats performing a visual orientation discrimination task after repeated experiences. These neurons showed stronger activities in correct-choice than incorrect-choice trials. These neurons efficiently represented low-contrast stimulations. Thus, the low-contrast preference in V1 activity may contribute to improved low-contrast visual. discrimination.

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Researchers reveal a novel mechanism that coordinates the assembly of components inside cells that control gene expression.

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A new article suggests that secondary antibodies known as 'anti-idiotype antibodies' could be responsible for some of the side effects of COVID-19 vaccines and the symptoms of long-haul COVID.

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Certain markers of injury to the brain's white matter, called white matter hyperintensities, can be seen on brain scans. A new study finds that brain scans taken during the lifetimes of athletes in contact sports, compared to changes in their brains at autopsy, showed that white matter hyperintensities were associated with neuropathological changes.

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New research that tested possible triggers of a common heart condition, including caffeine, sleep deprivation and sleeping on the left side, found that only alcohol use was consistently associated with more episodes of the heart arrhythmia.

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Just three minutes of exposure to deep red light once a week, when delivered in the morning, can significantly improve declining eyesight, finds a pioneering new study.

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