Infected tissue has a low concentration of oxygen. The body's standard immune mechanisms, which rely on oxygen, can then only function to a limited extent. How does the immune system nevertheless manage to control bacteria under such conditions? Researchers have discovered that fewer metabolites are produced in the citric acid cycle under hypoxic conditions, leading to a reduced rate of reproduction among bacteria in macrophages.

The mental health of children and young people with some long term physical conditions could benefit from cognitive behavioral therapy (CBT), according to a recent study. The systematic review used robust methods to bring together and make sense of the best science in this area.

Virtual reality (VR) can identify early Alzheimer's disease more accurately than 'gold standard' cognitive tests currently in use, new research suggests.

Leonardo da Vinci produced some of the world's most iconic art, but historical accounts show that he struggled to complete his works. New research now suggests the best explanation for Leonardo's inability to finish projects is that the great artist may have had attention deficit and hyperactivity disorder (ADHD).

The most severe pandemic in recent history, killing some 50 million people worldwide, the Spanish influenza, may have emerged up to two years earlier than previously believed. And, according to a new and influential study, its early manifestation was ignored at the time as a 'minor infection.'

A recent study offers an important step in unlocking the mystery of LHON's cause. The researchers had previously showed that the cells that connect the eye to the brain were sensitive to a certain free radical, known as 'superoxide,' and hypothesized that the presence of too much superoxide was likely the cause of LHON.

Testicular tissue samples obtained from 189 males who were facing procedures that could imperil fertility were cryopreserved at one university, proving the feasibility of centralized processing and freezing of testicular tissue obtained from academic medical centers scattered around the world.

With time, people can adapt to societal diversity and actually benefit from it, according to a new study. Those in power especially set the tone for integrating people into a new society.

Our doubts about what we think we know pique our curiosity and motivate us to learn more, according to new research.

Americans have a long tradition of taking to the streets to protest or to advocate for things they believe in. New research suggests that when it comes to climate change, these marches may indeed have a positive effect on the public.

Mitochondria, the 'batteries' that produce our energy, interact with the cell's nucleus in subtle ways previously unseen in humans, according to new research.

Research groups have solved a century-long puzzle about the presence of protein crystals in asthma. Normally, proteins do not crystallize in the body, but there are some instances where this process does occur.

A new study find women experiencing a minor stroke or transient ischemic attack (TIA) are less likely to be diagnosed with a stroke compared to men -- even though they describe similar symptoms in emergency departments.

Researchers have discovered a novel mechanism that ensures obstacle-free protein traffic into the powerhouse of the cell.