Researchers used single-nucleus RNA sequencing to compare transcriptional responses to acute cocaine in 16 unique cell populations from the brain nucleus accumbens. The atlas is part of a major study that used multiple cutting-edge technologies to describe a dopamine-induced gene expression signature that regulates the brain's response to cocaine. The study shows neurobiological processes that control drug-related adaptations and reveals new information about how transcriptional mechanisms regulate activity-dependent processes within the central nervous system.

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A new study found that remdesivir potently inhibited SARS-CoV-2, the virus which causes COVID-19, in human lung cell cultures and that it improved lung function in mice infected with the virus.

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A new article investigating the differences in CT findings between coronavirus disease (COVID-19) pneumonia and influenza virus pneumonia found that most lesions from COVID-19 were located in the peripheral zone and close to the pleura, whereas influenza virus was more prone to show mucoid impaction and pleural effusion. The more important role of CT during the present pandemic is in finding lesions and evaluating the effects of treatment.

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The CRISPR system is a powerful tool for the targeted editing of genomes, with significant therapeutic potential, but runs the risk of inappropriately editing ''off-target'' sites. However, a new study shows that mutating the enzyme at the heart of the CRISPR gene editing system can improve its fidelity.

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Researchers have found a significant increase in patients experiencing stress cardiomyopathy, also known as broken heart syndrome, during the COVID-19 pandemic.

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Researchers propose a decentralized, global wildlife biosurveillance system to identify -- before the next pandemic emerges -- animal viruses that have the potential to cause human disease.

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A new study of 2,500 Dutch children is the first to explore the relationship between brain volume and different doses of radiofrequency electromagnetic fields.

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Women who deliver their first child by cesarean section (C-section) are less likely to conceive a second child than those who deliver vaginally, despite being just as likely to plan a subsequent pregnancy, according to researchers. The team followed more than 2,000 women for three years after they delivered their first child.

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Researchers find that the benefits of inhalers for asthma sufferers outweigh the risks of contracting coronavirus, following concerns raised after WHO warned that steroids could reduce immunity.

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A little-studied liver protein may be responsible for the well-known benefits of exercise on the aging brain, according to a new study in mice. The findings could lead to new therapies to confer the neuroprotective effects of physical activity on people who are unable to exercise due to physical limitations.

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Findings from a new study into the effects of radiofrequency radiation generated by the wireless technology that will soon be the standard for cell phones suggest few health impacts.

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A new study might explain why humans register some tastes more quickly than others, potentially due to each flavor's molecular size. The research also provided explanation as to why humans register taste more quickly when food or drink moves over their tongues quickly, as compared to when they are held in their mouth steadily.

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Bats carry many viruses, including COVID-19, without becoming ill. Biologists are studying the immune system of bats to find potential ways to 'mimic' that system in humans.

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An international team of researchers has identified a chain of events that matures the sperm and triggers their motility. The findings have implications for diagnostic and therapeutic research in male infertility and male contraceptive development.

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A new paper examines the economics of an aquaculture industry of the future that is simultaneously environmentally sustainable and nutritious for the nearly 1 billion people worldwide who depend on it.

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